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The ability of D-2-deoxyglucose (2-DG) to interact with the hexose transport system in melanocytic neoplasms was studied by flow cytometry using mouse monoclonal antibodies directed against the hexose transporter. The 2-DG transport system, expressed in low percentages of melanocytes, was found to be higher in malignant melanomas than in other types of melanocytic neoplasms (moles and nevi). No significant differences in 2-DG transport were observed between primary melanoma, melanoma metastases and the compound nevi. This study suggests that, in the case of melanoma metastases and compound nevi, the process of selection for 2- ac619d1d87
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